Research

CELLIVIA research team conducts advanced research related to cell and tissue bioengineering, biotechnology and physico-chemistry.

Research based on cell biology and biotechnology consists of human cells primary cultures. These primary cultures are run in 2D and 3D systems.

Researchers cooperating with CELLIVIA have developed innovative and highly efficient methods of isolation and separation of specific cell types from human tissues based on mechanical and chemical methods. All isolated cell types are identified in terms of purity and homogeneity of the culture, using molecular genetics and flow cytometry methods. The most valuable, homogeneous primary cultures are immortalized using vector systems, thus creating established cell lines.

Primary cultures and established cell lines are mainly created from stem cells that are banked and stored for a long time after a given number of passages. Each time cells are planted, they are evaluated in terms of homogeneity and culture characteristics. CELLIVIA’s research task focus mainly on stem cells obtained from tissues of the reproductive system, oral cavity and teeth.

The goal of research carried out by CELLIVIA is to acquire, bank, and subsequently use for therapeutic purposes stem cells and methods associated with them, in regenerative and reconstructive medicine.

Research
lab

Research carried out by scientists cooperating with CELLIVIA are based in laboratories of cellular and molecular biology.

Laboratories are equipped with high-class, certified testing devices which guarantee that obtained results are reliable and can be transferred into clinical therapy and diagnostics.

Team is constantly improving research techniques used in routine laboratory work, for innovative and advanced methods of cellular bioengineering in regenerative medicine and physico-chemical chemistry in relation to the applicability of new/modified surfaces of dental biomaterials. The aim of CELLIVIA is to invest in technologically advanced equipment and conduct research at the highest scientific level.

Cooperation

CELLIVIA focuses on complementary development of industry and science.

Therefore, we cooperate with both scientific units and enterprises. Our goal is to carry out advanced research projects based on reliable cooperation with scientists representing scientific institutions at home and abroad.

CELLIVIA invests in human resources, expands know-how of cooperating individuals and scientists, and focuses on international cooperation involving exchange of experience and scientific ideas. CELLIVIA invests in new ideas and innovative technological solutions in medicine, biotechnology and bio-engineering. CELLIVIA cooperates, among others, with Poznań Science and Technology Park (PPNT) with which it conducts physical and chemical research on properties of biomaterials used, for example, in dentistry and orthopaedics.

CELLIVIA is open to Your ideas and proposals for long-term cooperation.

Training

CELLIVIA organizes trainings in advanced methods used in biomedicine, biotechnology, and bio-engineering.

Cooperation with a number of scientific institutions in Poland and abroad enables us to conduct highly specialized trainings carried out by prominent scientists in respective fields.

The training offer includes both theoretical classes, which are an essential introduction to scientific issues, as well as practical activities. Conducting training using modern infrastructure allows for implementation of highly specialized research methods. CELLIVIA training offer includes workshops on the basics of cell and molecular biology, based on the establishment and maintenance of primary 2D and 3D cell cultures, separation and long-term storage – cell banking. We want to share with You our experience in the field of stem cell culture from different germ layers, isolated from various human and animal tissues. CELLIVIA scientific team developed its own, modified and highly efficient methods of isolation and culture of primary selected human and animal cells. We make sure that trainings’ participants receive professional and fully up-to-date knowledge.

Due to conducting research in the field of dentistry and offering services related to this field, we want to regularly share with You our knowledge and experience in this area. Close cooperation with clinicians from the best centres in the country and abroad allows us to test our solutions in practice.

The main issues of our training are innovative methods used in medicine/regenerative and reconstructive dentistry. We put emphasis on the new possibilities of planning and treatment. The series of our trainings opens with the international conference “The art and science of dental treatment planning – innovative approach.”

Cyclic workshops and webinars available for registered participants will be a continuation of this project.

Together with the Medical University of Poznan and other scientific facilities in Poland and in Europe, we are beginning a series of postgraduate training in the field of imaging in dentistry.

We have prepared a post-graduate program in cooperation with Poznań Medical University and scientists from Poznań University of Technology in the following areas:

      1. Advanced Imaging and Interpretation in Maxillofacial Region
      2. Regenerative Medicine and Stem Cells Therapies
      3. Regenerative Dentistry
      4. Primary Cell Culture and Application of Biomaterials in Advanced Bioengineery and Medicine
      5. Human and Biological Robotics

Services

Cellivia research infrastructure has all necessary quality certificates with high level of biological safety.

We carry out assignments in the field of basic techniques of cell and molecular biology and physical and chemical bioengineering.

The scope of our research work includes:

      1. Isolation (mechanical and chemical) of cells from human and animal organs and tissues and establishment of primary cultures.
      2. Immortalization of primary cultures (creation of established cell lines), from the most valuable stem cell cultures originating from various germ layers.
      3. 2D and 3D cell cultures.
      4. Co-cultures of cells based on the technique of inserts (membranes limiting cell contacts, but allowing the exchange of compounds produced by them).
      5. Long-term primary cell culture.
      6. Cell banking.
      7. PCR
      8. Gene expression analysis based on the microarray expression technique (Affymetrix).
      9. Gene expression analysis based on the RT-qPCR technique.
      10. Identification of protein markers using flow cytometry.
      11. Identification of protein markers using LCMS-MS mass spectrometry.

We also offer assistance and interpretation of the results.

Contacts

str.Wilczak 45/47, 61-623, Poznan, Poland

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