med / choroby przyzębia

Therapies for periodontal diseases

Therapies for periodontal diseases The treatment methods available on the market often do not bring the expected results. As a rule, the symptoms of a disease can only be reduced for a short time yet, without lasting effects. There are no methods that would stimulate the regenerative mechanisms of the body.

Periodontal disease is a very common phenomenon.


The number of people in Poland suffering from periodontal diseases

The number of people diagnosed with severe periodontal disease

The number of people aged 33-44 with completely healthy teeth

Symptoms of the disease

Periodontal diseases are associated with gingival symptoms that include chronic or acute inflammation. The disease is accompanied by damage or destruction of the tissues that connect the tooth to the bone, such as periodontal ligaments. As a consequence, chronic periodontal disease can develop and destroy the bone. As the gums recede, bacteria build up in spaces called periodontal pockets, which over time turns the periodontal pockets into abscesses. As the disease progresses, the teeth become mobile and lose their functionality. A chronic infection may affect the general condition of a patient.

Treatment of periodontal diseases

Treatment of periodontal disease varies according to their severity. Good oral hygiene, including regular brushing and flossing, can reverse mild periodontitis. A dentist can also thoroughly clean, probe and stimulate the periodontal pockets. In more severe cases, the patient is given topical oral antibiotics and sometimes surgical intervention is performed, which not always proves successful. In many cases, treatment of periodontal disease is difficult and does not bring the expected outcomes, which results in early loss of the teeth.

Currently available treatment methods often do not bring the desired results. Generally speaking, the symptoms of the disease can be reduced temporarily. There are no methods that would stimulate the regenerative mechanisms of the body.

Exosomes in periodontal diseases

Exosomes taken from mesenchymal stem cells (MSCs) promote the regeneration of periodontal tissues, aid the formation of a new bone and regeneration of periodontal ligaments. Scientists also found that exosomes are able to recruit new patient cells to replace the damaged ones. Through the mechanism of increased cell infiltration and proliferation, exosomes stimulate the regeneration of the damaged tissues.

Therefore, exosomes can be considered a ready-to-use and cell-free MSC-based agent for the treatment of periodontal diseases.